Cyproheptadine adverse drug interaction with anti-epileptic drugs
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چکیده
منابع مشابه
Ketamine and e.e.g. seizure waves: interaction with anti-epileptic drugs.
When unrestrained cats were with ketamine 2-6 mg kg-1 i.v., anaesthesia was associated with seizure waves induced in the cortical e.e.g. After cats were pretreated with trimethadione 500 mg kg-1 i.p., ketamine did not induce seizure waves. Pretreatment with diphenylhydantoin 25 or 100 mg kg-1 i.p. slightly enhanced seizure waves following ketamine. In both situations the anaesthetic effect of k...
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Journal of the Malta College of Pharmacy Practice 23 In this paper an overview will be given of how knowledge of pharmacokinetic mechanisms determines which pharmacokinetic characteristics an AED should have. Various clinical factors such as age, underlying physiological conditions and drug interactions will also affect the pharmacokinetics and efficacy of AED medication. It will be shown how b...
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Use of medication with a desired effect on the central nervous system (as with anti-epileptic drugs) in children will undoubtedly cause concern about neurodevelopment. Data are emerging to suggest an effect of anticonvulsants on the developing brain of the unborn child when administered to mothers with epilepsy. This obviously requires detailed evaluation, especially when considering the risks ...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2018
ISSN: 2279-0780,2319-2003
DOI: 10.18203/2319-2003.ijbcp20180677